Nonoxynol-9 is a spermicidal active ingredient available in over-the-counter (OTC) medicines that help prevent pregnancy by killing sperm.

Nonoxynol-9 is approved by the U.S. Food and Drug Administration (FDA) and is safe. It has been found to be most effective when used as directed. Vaginal contraceptive products containing nonoxynol-9 do not protect against HIV, AIDS, or other sexually transmitted diseases. If you do not know if you or your partner is HIV-infected, you should choose another form of birth control.

  • You recently had a miscarriage or abortion.
  • You have been told you should not become pregnant.
  • You are breastfeeding.
  • You have a vaginal or uterine condition, such as vaginal septum or uterine prolapse.
  • You have a new sexual partner, multiple partners, or unprotected sex.
  • You are pregnant or think you might be pregnant.
  • You have given birth within the past six weeks.
  • You or your partner has HIV or AIDS.
  • You are allergic to nonoxynol-9.
  • The product packaging is torn or appears to have been tampered with.
  • You or your partner experience burning, itching, a rash, or other genital irritation.
  • You or your partner are having difficulty urinating or are experiencing painful urination.
  • You develop abdominal pain, fever, chills, or a foul-smelling vaginal discharge.
  • You become pregnant.
  • You accidentally swallow the product. Immediately contact a healthcare provider or the poison control national helpline at 800.222.1222.