Pheniramine (also referred to as pheniramine maleate) is an antihistamine available in both oral and topical forms and is used to treat a number of different conditions. Oral pheniramine is found in multi-symptom over-the-counter (OTC) medicines used to alleviate symptoms due to hay fever, or other upper respiratory as well as cold symptoms. Topically applied pheniramine can relieve redness and itchy eyes caused by pollen, ragweed, grass, animal hair and dander, and other eye allergens.

Pheniramine is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to the Drug Facts label directions. Because OTC medicines containing pheniramine are combined with other active ingredients in oral multi-symptom cold/hay fever products and topical eye allergy medicines, you should read the Drug Facts label for a complete listing of all of the product’s ingredients and always follow the directions.

 

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Pheniramine Safe Use Tips

  • You do not know if your prescription drug contains a monoamine oxidase inhibitor (MAOI).
  • You have a breathing problem such as emphysema, asthma, or chronic bronchitis.
  • You have trouble urinating due to an enlarged prostate gland.
  • You have heart disease, high blood pressure, diabetes, glaucoma, or thyroid disease.
  • You are pregnant or breastfeeding.
  • You are currently taking a prescription monoamine oxidase inhibitor (MAOI) or if you stopped taking an MAOI less than two weeks ago.
  • You are taking a prescription drug for depression, a psychiatric or emotional condition, or Parkinson’s disease.
  • You take too much. Immediately contact a healthcare provider or the poison control national helpline at 800.222.1222.
  • Talk to a healthcare provider before giving an OTC cold medicine with an antihistamine to a child under the age of 6.
  • Never use pheniramine or any OTC medicine to sedate or make a child sleepy.
  • Click here for more information on giving OTCs to children.

Pheniramine-Containing Eye Allergy Medicines

  • In order to avoid contamination, you should not touch the tip of the eye drop dispenser to any surface.
  • You should remove contact lenses before use.
  • You may feel a brief tingling after putting the medicine in your eye.
  • You have heart disease, high blood pressure, or narrow angle glaucoma.
  • You have trouble urinating due to an enlarged prostate gland.
  • You are sensitive to pheniramine.
  • The medicine solution changes color or becomes cloudy.
  • You accidentally swallow the medicine. Immediately contact a healthcare provider or the poison control national helpline at 800.222.1222.
  • You experience eye pain or changes in vision.
  • You have redness or irritation that gets worse or lasts for more than 72 hours.
  • Talk to a healthcare provider before using a topical OTC eye allergy medicine containing pheniramine on a child under the age of 6.