Tioconazole is an antifungal available in over-the-counter (OTC) medicines that treat vaginal yeast infections. Tioconazole is available in single-ingredient vaginal yeast infection products.

Tioconazole is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to label directions. If you are experiencing vaginal itching or discomfort for the first time and have never been properly diagnosed for a vaginal yeast infection, you should see a healthcare provider before using an OTC vaginal product containing tioconazole.

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  • You have lower-abdominal, back, or shoulder pain; fever; chills; nausea; vomiting; or a foul-smelling vaginal discharge.
  • You have vaginal yeast infections often, such as three in six months.
  • You are pregnant or breastfeeding.
  • You could be pregnant or have a serious underlying medical condition that may be causing your symptoms, including diabetes or a weakened immune system.
  • You have been exposed to the human immunodeficiency virus (HIV) that causes AIDS.
  • You have never had a vaginal yeast infection diagnosed by a healthcare provider.
  • The product’s foil packet is torn, open, or incompletely sealed.
  • Your symptoms do not get better within three days or the infection lasts for more than seven days.
  • You get a rash or hives, abdominal pain, fever, chills, nausea, vomiting, or a foul-smelling vaginal discharge.
  • You accidentally swallow the medicine. Immediately contact a healthcare provider or the poison control national helpline at 800.222.1222.
  • Do not use a vaginal product containing tioconazole on a child under the age of 12.
  • Do not use a vaginal product containing tioconazole on a child over the age of 12 if the child has never had a vaginal yeast infection properly diagnosed by a healthcare provider.
  • Contact a healthcare provider if you have any questions or concerns about the symptoms your child is experiencing.