Updated Cardiovascular Warning on Non-aspirin NSAIDs

The U.S. Food and Drug Administration (FDA) has amended the existing cardiovascular warning on non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), including the active ingredients ibuprofen, ketoprofen (Rx only), magnesium salicylate, and naproxen sodium to state that these medicines can increase the risk of heart attack or stroke. The risk is higher if you use more than directed or for longer than directed. The updated warning does not apply to aspirin. The change was first applied to prescription products and a similar change is now appearing on over-the-counter (OTC) NSAIDs Drug Facts labels, with the exception of aspirin.

To ensure you are safely using non-aspirin OTC NSAIDs to treat your minor pain and fever, read and follow the Drug Facts label and talk to your healthcare provider if you have any questions. Also, consumers should be aware that NSAIDs are an active ingredient in many medicines – both prescription and OTC – and ensure they aren’t inadvertently taking more than the recommended dose.

Find more information about safe use of OTC NSAIDs here.