Pseudoephedrine is a nasal decongestant active ingredient available in over-the-counter (OTC) medicines that relieve a stuffy nose or sinus pressure due to the common cold or other ailments. It may be written as pseudoephedrine, pseudoephedrine hydrochloride (HCl), or pseudoephedrine sulfate, but each has the same effect in the human body. Pseudoephedrine can be the only active ingredient in a nasal decongestant medicine or it can be found in medicines that not only relieve a stuffy nose, but other symptoms as well such as allergies, headache, or cough.
Pseudoephedrine is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to Drug Facts label. If you have a pre-existing health condition like high blood pressure or heart disease, check with a healthcare provider before using a medicine containing pseudoephedrine.