Ranitidine is an acid reducer available in over-the-counter (OTC) medicines that relieve or prevent heartburn symptoms associated with acid indigestion and sour stomach. It may be written as ranitidine or ranitidine hydrochloride, but it is the same active ingredient. Ranitidine is part of a group of acid reducers called histamine-2 antagonists, or H2 blockers.
Ranitidine is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to the Drug Facts label directions. If you have kidney disease, you should not use an OTC containing ranitidine, unless you are under the advice and supervision of a healthcare provider.